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cryopreserved human bone marrow stromal cells  (STEMCELL Technologies Inc)

 
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    Structured Review

    STEMCELL Technologies Inc cryopreserved human bone marrow stromal cells
    A Exploded view of the HUMIMIC Chip2 showing the three structural layers. B 2D view of the HUMIMIC Chip2 microfluidics: the outer compartment houses the <t>bone</t> <t>marrow</t> model; the inner compartment is used as a medium reservoir and as a sampling point for hematopoietic <t>cells.</t> C Calcein-AM RedOrange staining (red) of vital mesenchymal <t>stromal</t> cells populating the ceramic, scale is 250 µm. D The top 20 enriched GO BP terms in MSC samples from static and dynamic cultivation in MSC and HSC cultivation medium. Only GO BP terms from a list of GO biological processes significantly enriched among osteocyte transcriptome signature genes according to Youlten et al. were considered. E Dimensionality reduction of the gene expression profiles using PCA. The PCA is computed based on the top 500 most variable genes using TMM-normalized logCPM. Arrows indicate time course of the experiment. F GO biological processes enrichment analysis for differential expressed genes in different MSC culture conditions. Signatures correspond to rows and indications/contrasts to columns. The color shows the median log2 fold-changes of the genes in the signatures. Significance level is indicated with asterisks: *** 1% FDR, ** 5% FDR, *10% FDR.
    Cryopreserved Human Bone Marrow Stromal Cells, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cryopreserved+human+bone+marrow+stromal+cells/cryopreserved+human+bone+marrow+stromal+cells/pmc12081850-386-1-6
    Average 90 stars, based on 1 article reviews
    cryopreserved human bone marrow stromal cells - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "A microfluidic bone marrow chip for the safety profiling of biologics in pre-clinical drug development"

    Article Title: A microfluidic bone marrow chip for the safety profiling of biologics in pre-clinical drug development

    Journal: Communications Biology

    doi: 10.1038/s42003-025-08137-1

    A Exploded view of the HUMIMIC Chip2 showing the three structural layers. B 2D view of the HUMIMIC Chip2 microfluidics: the outer compartment houses the bone marrow model; the inner compartment is used as a medium reservoir and as a sampling point for hematopoietic cells. C Calcein-AM RedOrange staining (red) of vital mesenchymal stromal cells populating the ceramic, scale is 250 µm. D The top 20 enriched GO BP terms in MSC samples from static and dynamic cultivation in MSC and HSC cultivation medium. Only GO BP terms from a list of GO biological processes significantly enriched among osteocyte transcriptome signature genes according to Youlten et al. were considered. E Dimensionality reduction of the gene expression profiles using PCA. The PCA is computed based on the top 500 most variable genes using TMM-normalized logCPM. Arrows indicate time course of the experiment. F GO biological processes enrichment analysis for differential expressed genes in different MSC culture conditions. Signatures correspond to rows and indications/contrasts to columns. The color shows the median log2 fold-changes of the genes in the signatures. Significance level is indicated with asterisks: *** 1% FDR, ** 5% FDR, *10% FDR.
    Figure Legend Snippet: A Exploded view of the HUMIMIC Chip2 showing the three structural layers. B 2D view of the HUMIMIC Chip2 microfluidics: the outer compartment houses the bone marrow model; the inner compartment is used as a medium reservoir and as a sampling point for hematopoietic cells. C Calcein-AM RedOrange staining (red) of vital mesenchymal stromal cells populating the ceramic, scale is 250 µm. D The top 20 enriched GO BP terms in MSC samples from static and dynamic cultivation in MSC and HSC cultivation medium. Only GO BP terms from a list of GO biological processes significantly enriched among osteocyte transcriptome signature genes according to Youlten et al. were considered. E Dimensionality reduction of the gene expression profiles using PCA. The PCA is computed based on the top 500 most variable genes using TMM-normalized logCPM. Arrows indicate time course of the experiment. F GO biological processes enrichment analysis for differential expressed genes in different MSC culture conditions. Signatures correspond to rows and indications/contrasts to columns. The color shows the median log2 fold-changes of the genes in the signatures. Significance level is indicated with asterisks: *** 1% FDR, ** 5% FDR, *10% FDR.

    Techniques Used: Sampling, Staining, Gene Expression



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    cryopreserved human bone marrow stromal cells  (STEMCELL Technologies Inc)
    90
    STEMCELL Technologies Inc cryopreserved human bone marrow stromal cells
    A Exploded view of the HUMIMIC Chip2 showing the three structural layers. B 2D view of the HUMIMIC Chip2 microfluidics: the outer compartment houses the <t>bone</t> <t>marrow</t> model; the inner compartment is used as a medium reservoir and as a sampling point for hematopoietic <t>cells.</t> C Calcein-AM RedOrange staining (red) of vital mesenchymal <t>stromal</t> cells populating the ceramic, scale is 250 µm. D The top 20 enriched GO BP terms in MSC samples from static and dynamic cultivation in MSC and HSC cultivation medium. Only GO BP terms from a list of GO biological processes significantly enriched among osteocyte transcriptome signature genes according to Youlten et al. were considered. E Dimensionality reduction of the gene expression profiles using PCA. The PCA is computed based on the top 500 most variable genes using TMM-normalized logCPM. Arrows indicate time course of the experiment. F GO biological processes enrichment analysis for differential expressed genes in different MSC culture conditions. Signatures correspond to rows and indications/contrasts to columns. The color shows the median log2 fold-changes of the genes in the signatures. Significance level is indicated with asterisks: *** 1% FDR, ** 5% FDR, *10% FDR.
    Cryopreserved Human Bone Marrow Stromal Cells, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cryopreserved+human+bone+marrow+stromal+cells/cryopreserved+human+bone+marrow+stromal+cells/pmc12081850-386-1-6
    Average 90 stars, based on 1 article reviews
    cryopreserved human bone marrow stromal cells - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    A Exploded view of the HUMIMIC Chip2 showing the three structural layers. B 2D view of the HUMIMIC Chip2 microfluidics: the outer compartment houses the bone marrow model; the inner compartment is used as a medium reservoir and as a sampling point for hematopoietic cells. C Calcein-AM RedOrange staining (red) of vital mesenchymal stromal cells populating the ceramic, scale is 250 µm. D The top 20 enriched GO BP terms in MSC samples from static and dynamic cultivation in MSC and HSC cultivation medium. Only GO BP terms from a list of GO biological processes significantly enriched among osteocyte transcriptome signature genes according to Youlten et al. were considered. E Dimensionality reduction of the gene expression profiles using PCA. The PCA is computed based on the top 500 most variable genes using TMM-normalized logCPM. Arrows indicate time course of the experiment. F GO biological processes enrichment analysis for differential expressed genes in different MSC culture conditions. Signatures correspond to rows and indications/contrasts to columns. The color shows the median log2 fold-changes of the genes in the signatures. Significance level is indicated with asterisks: *** 1% FDR, ** 5% FDR, *10% FDR.

    Journal: Communications Biology

    Article Title: A microfluidic bone marrow chip for the safety profiling of biologics in pre-clinical drug development

    doi: 10.1038/s42003-025-08137-1

    Figure Lengend Snippet: A Exploded view of the HUMIMIC Chip2 showing the three structural layers. B 2D view of the HUMIMIC Chip2 microfluidics: the outer compartment houses the bone marrow model; the inner compartment is used as a medium reservoir and as a sampling point for hematopoietic cells. C Calcein-AM RedOrange staining (red) of vital mesenchymal stromal cells populating the ceramic, scale is 250 µm. D The top 20 enriched GO BP terms in MSC samples from static and dynamic cultivation in MSC and HSC cultivation medium. Only GO BP terms from a list of GO biological processes significantly enriched among osteocyte transcriptome signature genes according to Youlten et al. were considered. E Dimensionality reduction of the gene expression profiles using PCA. The PCA is computed based on the top 500 most variable genes using TMM-normalized logCPM. Arrows indicate time course of the experiment. F GO biological processes enrichment analysis for differential expressed genes in different MSC culture conditions. Signatures correspond to rows and indications/contrasts to columns. The color shows the median log2 fold-changes of the genes in the signatures. Significance level is indicated with asterisks: *** 1% FDR, ** 5% FDR, *10% FDR.

    Article Snippet: Cryopreserved human bone marrow stromal cells (Stemcell Technologies, Vancouver, BC, Canada) were thawed and initially seeded at a density of 1750 cells/cm 2 in T175 cell culture flasks in Mesencult-ACF Plus medium (Stemcell Technologies, Vancouver, BC, Canada).

    Techniques: Sampling, Staining, Gene Expression